Diet, sun exposure and arthritis: a forgotten study confirms what we know now.

Sun exposure By Marc Sorenson, EdD… Sunlight Institute…

Nearly thirty years ago, I talked to many “experts” who told me that our mostly vegetarian diet could not help those who suffered from arthritis, because “diet has nothing to do with arthritis.” However, I was able to find one or two pieces of research that indicated that arthritis was indeed associated with poor nutrition and could be ameliorated or reversed by proper nutritional habits.

Then, during our many years in the health and fitness resort business, we observed many seeming miracles with our arthritic attendees. One woman, who could not play piano due to her arthritic hands, was able to play again in less than two weeks. Her reduction in inflammation was visible and her increase in range-of motion was remarkable. Her husband, who could not walk more than about a hundred yards when they arrived, was walking a mile after two weeks as his arthritic hips recovered range of motion and his muscles gained strength.

Through serendipity, a few days ago, a piece of research appeared to me—a study that I wished I had known about 30 years ago. It was published in 1935, and was titled, THE TREATMENT OF CHRONIC ARTHRITIS BY DIET AND SUNLIGHT.[1] The author studied a group of seventy-two arthritic patients whom he treated with diet, calling his program the “depletion diet.” The diet was bulky and very high in protective foods, but contained very little protein and fat. He stated that “Thus in seventy-two cases treated by diet, five were not improved, thirteen were slightly improved, thirty-nine were much improved, and fifteen were completely relieved.”

Other treatment included sunbathing, and the doctor considered it so important that he had his patients move to an area where they could sunbathe for at least eight weeks per year. He felt that it was almost indispensable.

Our program was somewhat similar, although our diet was much stricter. We were fortunate that we already operated our resort in an area where the sun shines about 260 days per year.

Other research has shown a correlation between arthritis and sun exposure. A paper by Dr. Viera and colleagues demonstrated that at high latitudes, where sun exposure is considerably less available, the rate of rheumatoid arthritis (RA) is much higher than at lower latitudes.[2]  RA is also more severe in winter,[3] a time of less sun exposure.

So give up the junk food and safely embrace the sun. Your joints will love it!

[1] Langsworth, L. THE TREATMENT OF CHRONIC ARTHRITIS BY DIET AND SUNLIGHT. CALIFORNIA AND WESTERN MEDICINE. March, 1935.

[2]Vieira VM, Hart JE, Webster TF, Weinberg J, Puett R, Laden F, Costenbader KH, Karlson EW. Association between Residences in U.S. Northern Latitudes and Rheumatoid Arthritis: A Spatial Analysis of the Nurses’ Health Study. Environ Health Perspect. 2010 Mar 25. [Epub ahead of print]

[3]Cutolo M, Otsa K, Uprus M, Paolino S, Seriolo B.  Vitamin D in rheumatoid arthritis.  Autoimmun Rev 2007;7:59-64

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More Truth about Sun Exposure

By Marc Sorenson, EdD… Sun exposure benefits…

A very important paper regarding the necessity for sun exposure has recently been published by the journal Medical Hypothesis.[1] It is entitled Regular sun exposure benefits health, and it discusses the pros and cons of sun exposure. One of the salient statements in the paper is that intermittent sun exposure may increase the risk of skin cancer, whereas regular exposure to sunlight might benefit health. For those of us who have for years studied the beneficial effects of sun exposure, the use of the word “might” is the only drawback to the statement. There is no doubt that for the majority of the population, regular sun exposure absolutely protects and enhances health.

Among the diseases mentioned as being reduced or prevented by regular sun exposure are the following:

  1. Cancers: Colon, breast, prostate and non-Hodgkin lymphoma
  2. Multiple sclerosis
  3. Hypertension
  4. Diabetes

As the authors mention, most of these positive effects of sun exposure were previously ascribed to Vitamin D, but they point out that immune system function is enhanced by sun exposure beyond the effects of vitamin D, and list other non-vitamin D benefits of the sun, including:

  1. Production of nitric oxide
  2. Production of melatonin
  3. Production of serotonin
  4. Regulation of the circadian clock

I have discussed most of these items on the Sunlight Institute web site, but it was good to see new research that, in particular, separated the health benefits of sun exposure from vitamin D production. The idea that has become popularized during the past decade, that all benefits of sun exposure come from increased vitamin D production, is simply not true and can lead to the supplementation of vitamin D as a “cure” for diseases that may not be influenced by that hormone.

Of course, vitamin D is an exceptionally important photoproduct, and the only natural way to attain it is by exposure to the sun or to other sources of UVB light (such as a sunlamp or a tanning bed). The beauty of using these sources, rather than a vitamin-D capsule, is that all of the benefits of nitric oxide, melatonin, serotonin and circadian entrainment are included in the package.

Safely enjoy the sun, and you then will also safely enjoy better health. Remember not to burn, and to gradually develop a good tan.

[1]  van der Rhee H, de Vries, E, Coebergh, J. Regular sun exposure benefits health. Medical Hypotheses 97 (2016) 34–37

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Sun Exposure may be superior to Vitamin D for reducing Colon-Cancer Risk.

The importance of sun exposure for colon cancer

By Marc Sorenson, EdD, Sunlight Institute…

In 1980, Cedric and Frank Garland published a seminal paper showing a relationship between colon cancer and geographical location.[1] They observed dramatically higher rates of colon cancer in the Northeast, where there is a paucity of sun exposure, compared with the South and West where sun is more prevalent. They hypothesized that vitamin D, stimulated in the skin by sun, reduced the risk of colon cancer. They pointed out the correlation between colon cancer and UVR exposure, stating particularly that “New Mexico and Arizona had the highest statewide mean solar radiation values (500 gm-cal/cm2). These states experienced colon cancer rates for white males of 6.7 and 10.1 per 100 000 population, respectively, over the period 1959–61.  New York, New Hampshire, and Vermont had the lowest statewide mean solar radiation values (300 gm-cal/cm2) and experienced colon cancer rates for white males of 17.3, 15.3, and 11.3 per 100 000 populations, respectively, during the same period.”

Other studies have corroborated the correlation between high sun exposure and low colon cancer rates. Japanese research demonstrated that people in the areas of highest solar radiation exhibit the lowest rates of colon cancer, with those living in the areas of highest sun exposure having about half the colon cancer rate as those living in the lowest.[2]A significant aspect of this research is that sun correlated to a reduced risk of cancer even where vitamin D consumption was high, indicating that sun exposure (as noted with prostate cancer and breast cancer, above) may have beneficial influences on cancer beyond its stimulation of vitamin D production, or that vitamin D produced in the skin by sun exposure may have advantages over that consumed through food or supplements. 

The research by Dr. Mizoue is not the only investigation that differentiated the effects of UV light exposure and vitamin D/colon cancer. A six-week study by Dr. Rebel and colleagues used mice with intestinal tumors—tumors that often progress to cancers.[3] It was shown that the mice given either UV radiation or vitamin-D supplementation reduced the tumor load when compared to mice who received no treatment. However, only the UV treatments prevented the tumors from progressing to cancer. Still other recent research has demonstrated that sun, not vitamin D, may produce all of the positive effects on colon cancer. The researchers performed a 140-day investigation involving rats that had colon adenomas (a precursor to full-blown colon cancer) induced in their colons.[4] The rats were given either vitamin D3 as supplements, or the stored form of vitamin D, 25(OH)D3, in differing amounts. With low dose vitamin D in either form, no reduction in either existing adenomas or emerging tumors were seen. In higher doses, there was a dose-dependent increase in colon tumor numbers in both male and female rats. The researchers said the following in their concluding statement: “Thus, the association between sun exposure and the incidence of colon cancer may involve factors other than vitamin D concentrations. Alternative hypotheses warrant investigation. Furthermore, this study provides preliminary evidence for the need for caution regarding vitamin D supplementation of humans at higher doses, especially in individuals with sufficient serum 25(OH)D3 concentrations.” The takeaway from this research is this: sun is protective against colon cancer in rats (and probably in humans), independent of vitamin D—another reason to safely embrace the sun.

These studies again demonstrate that we cannot substitute vitamin D pills for sun in many cases. UV light from sun or sun lamps is always the best option to cover all prevention and healing possibilities.

[1] Garland CF, Garland FC. Do sun and vitamin D reduce the likelihood of colon cancer?  Int. J. Epidemiol 1980;9:227–31.

[2] Mizoue, T.  Ecological study of solar radiation and cancer mortality in Japan.  Health Phys 2004;87:532-38.

[3] Rebel H1, der Spek CD, Salvatori D, van Leeuwen JP, Robanus-Maandag EC, de Gruijl FR. UV exposure inhibits intestinal tumor growth and progression to malignancy in intestine-specific Apc mutant mice kept on low vitamin D diet. Int J Cancer. 2015 Jan 15;136(2):271-7.

[4] Irving AA, Plum LA, Blaser WJ, Ford MR, Weng C, Clipson L, DeLuca HF, Dove WF. Cholecalciferol or 25-hydroxycholecalciferol neither prevents nor treats adenomas in a rat model of familial colon cancer. J Nutr. 2015 Feb;145(2):291-8.

 

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Sun Exposure reduces Obesity; Vitamin D does not.

By Marc Sorenson, EdD. Sunlight Institute…

Sun exposure reduces the risk of obesity, and that relationship has been credited to vitamin D. However, one study, conducted on mice, shows that vitamin D may have nothing to do with reducing or preventing obesity.[1] The animals were placed on a high-fat diet to cause obesity. Then they were subjected to long-term exposure to ultraviolet radiation (UVR), (which is the same sunlight spectrum that leads to the production of vitamin D and other photoproducts). The UVR significantly suppressed weight gain and other measures of the metabolic syndrome (MetS), including glucose intolerance, insulin resistance, fasting insulin levels, fatty liver disease and serum cholesterol levels.

Interestingly, when the animals were supplemented with vitamin D, no such benefits occurred, meaning that UVR created the positive protections independently. However when nitric oxide was applied to the skin of the animals, the positive effects on weight loss and metabolic syndrome were again observed. Nitric oxide, of course, is another photoproduct of sun exposure, which has many positive health effects.

Other research showed that early-morning sun exposure was correlated to lower body-mass index (BMI) which is a measure of body fatness.[2] The authors of that research suggested that the mechanisms involved in weight control by early light exposure could be the following: (1) resetting the circadian rhythm (internal clock), (2) the greater quantity of blue light in morning sun and (3) effects on melatonin production. Whatever the mechanisms, we now know that early-morning sun is important to weight control. It may also be important to other health issues. But before we begin to think that sun exposure is the cure-all for obesity, realize that poor nutritional habits and lack of exercise are much more important. Nevertheless, sun exposure can furnish one more arrow in the quiver of protection from obesity.

Get your sun exposure and stay slim! Be careful not to burn.

[1] Geldenhuys S, Hart PH, Endersby R, Jacoby P, Feelisch M, Weller RB, Matthews V, Gorman S. Ultraviolet radiation suppresses obesity and symptoms of metabolic syndrome independently of vitamin D in mice fed a high-fat diet. Diabetes. 2014 Nov;63(11):3759-69.

[2] Reid KJ, Santostasi G, Baron KG, Wilson J, Kang J, Zee PC. Timing and intensity of light correlate with body weight in adults. PLoS One 2014;2;9(4)

 

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Both vitamin D and Sun Exposure suppress Inflammatory Bowel Disease.

By Marc Sorenson, EdD, Sunlight Institute..

Inflammatory bowel diseases (IBD) include diseases such as Crohn’s disease and ulcerative colitis. Like multiple sclerosis, lupus and rheumatoid arthritis, they are autoimmune diseases that cause the immune system to attack its own tissue, in this case the tissues of the digestive system. This may cause extreme distress and damage.

Recent research shows that the IBD is associated with both sun exposure and vitamin D deficiency.[1] In experimental IBD, vitamin D positively influences gut epithelial cells, innate immune cells, T cells, and the microscopic organisms that live in the gut. Separately from vitamin D, there is some scientific work that demonstrates that ultraviolet radiation (UVR), a component of sun exposure, can independently reduce IBD cells.

The authors of this research sum up their research with the following statement: “Together the data suggest that UVR suppression of T cells and potentially IBD are both vitamin D dependent and independent.”

Of course, we know that the natural way to obtain vitamin D is through sun exposure, so to me it appears that sun exposure, or sunlamp exposure, when available is the best method of suppressing the disease. Of course, proper nutrition is also imperative.

Many previous investigations have shown the remarkable positive influence of sun exposure on IBD. In a 12-year year investigation of hundreds of thousands of IBD patients, hospitalizations and prolonged hospitalizations were higher among those who had low sun exposure compared to those with very high sun exposure.[2] The same relationship was shown between sun, bowel surgeries and deaths; more surgeries were needed for those patients who experienced the lowest sun exposure compared to those who had the highest sun exposure, and more deaths occurred among those with low exposure.

An interesting side note to this investigation was that a large number of non-IBD patients were also analyzed for sun exposure amounts. The same relationship existed as with the IBD patients; low sun exposure was associated with prolonged hospitalizations and more deaths when compared with high exposure. There is other research involving the association of Crohn’s disease to sun exposure, which, as above, found that surgery for the disease was significantly reduced among those patients who received more sun exposure.[3]

It has also been shown that in the US, there is a north-south gradient for IBD,[4] [5] [6] [7] meaning that the risk of developing IBD is significantly lower for the southern latitudes (where sun exposure is greater). So for a healthy gut, sun exposure plays a vital role. Be sure to get some sun exposure daily when available. That way, you will obtain your vitamin D, along with other photoproducts that may protect you from IBD as well as myriad other diseases.

 

 

[1] Bora S, Cantorna MT. The role of UVR and vitamin D on T cells and inflammatory bowel disease. Photochem Photobiol Sci. 2016 Sep 8. [Epub ahead of print].

[2]Limketkai BN, Bayless TM, Brant SR, Hutfless SM. Lower regional and temporal ultraviolet exposure is associated with increased rates and severity of inflammatory bowel disease hospitalization. Aliment Pharmacol Ther. 2014 Sep;40(5):508-17.

[3]Govani SM, Higgins PD, StidhamRW,Montain SJ, Waljee AK.Increased ultraviolet light exposure is associated with reduced risk of inpatient surgery among patients with Crohn’s disease.J Crohns Colitis. 2015 Jan;9(1):77-81

[4] Schultz M1, Butt AG. Is the north to south gradient in inflammatory bowel disease a global phenomenon? Expert Rev Gastroenterol Hepatol. 2012 Aug;6(4):445-7.

[5]Kappelman MD, Rifas-Shiman SL, Kleinman K, Ollendorf D, Bousvaros A, Grand RJ, Finkelstein JA. The prevalence and geographic distribution of Crohn’s disease and ulcerative colitis in the United States. Clin Gastroenterol Hepatol. 2007 Dec;5(12):1424-9.

[6]Sonnenberg A. Similar geographic variations of mortality and hospitalization associated with IBD and Clostridium difficile colitis. Inflamm Bowel Dis. 2010 Mar;16(3):487-93.

[7]Holmes EA, Xiang F, Lucas RM. Variation in incidence of pediatric Crohn’s disease in relation to latitude and ambient ultraviolet radiation: a systematic review and analysis.Inflamm Bowel Dis. 2015 Apr;21(4):809-17

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Athletic performance and sun exposure.

Athletic Performance and sun exposure.

Almost no one realizes the dramatic improvement that sun exposure can make on athletic performance. Years ago I helped Dr. John Cannell obtain translations of many esoteric and decades-old studies that had been forgotten, probably due to the fact that sun lamps were used to create some of the improvements in athletics, and have fallen out of favor due to the sunscare movement. I co-authored a paper with Cannell, called Athletic Performance and Vitamin D.[1] That paper is the source of much of the material covered here, and it demonstrates the remarkable, positive effect of sun or other ultraviolet (UV) exposure on human performance. I would also strongly suggest that the readers avail themselves of Dr. Cannell’s book on the subject, called The Athlete’s Edge, which discusses in far greater detail the materials introduced here.

One of the salient studies on UV exposure took place in 1957 and assessed the influence of sun exposure on strength and performance over a two-year period.[2] During that time six subjects were able to increase athletic performance and muscle trainability through systematic UV exposure. But when vitamin D3 was used, it not only did not work, it inhibited the performance-enhancing effect of the UV. I sometimes fear the public is beginning to believe that if sun exposure is proven to enhance human health, one needs only to take a vitamin D pill. Don’t get pulled into that idea. Sun exposure will always be more important than any of the photoproducts whose production it stimulates.

Here are some of the other salient studies on sun exposure and performance. In 1938, Russian researchers demonstrated that a series of four UV treatments improved speed in the 100-meter dash compared to four non-irradiated students, when both groups were undergoing daily physical training.[3] The times improved from 13.51 seconds to 13.28 seconds in the non-irradiated group and from 13.63 to 12.62 seconds in the irradiated group. In other words, the UV-treated group improved by three-fourths of a second more than the non-UV group. That may seem like a relatively small improvement, but three-fourths of a second better time in a 100-meter dash could be the difference between first and last place!

German research from 1944 showed that the exposure of 32 medical students to UV, twice weekly during for six weeks, associated with a 13% improvement in endurance, whereas performance of a control group was unchanged.[4]

Other German research shows that the ability of a muscle to gain strength (trainability) is much better in summer than winter, and peaks in September.[5] In fact, the trainability in September was 2½ times higher than the average monthly trainability for the entire year.

So you who love athletics, don’t avoid the sun. It may make you a winner. But don’t burn.

Reaction time has also been shown to improve significantly in the sunnier months.[6] [7]

When we consider reaction time, muscle and bone strength, speed and endurance, we should realize that these measurements are not only important for athletes; they are important for all aspects of living for all people. Everyone wants to be stronger, quicker, and faster, as well as have more endurance in daily activities. So embrace the sun, but do it safely and don’t burn.

 

[1] Cannell JJ, Hollis BW, Sorenson MB, Taft TN, Anderson JJ. Athletic performance and vitamin D. Med Sci Sports Exerc. 2009 May;41(5):1102-10.

[2] E. Seidl and Th. Hettinger. The Effect of Vitamin D3 on the Strength and Performance of a Healthy Adult. International Journal Physiology, including Industrial Physiology, Vol. 16, Pages 365-372 (1957).

[3] Gorkin Z, Gorkin MJ, Teslenko NE. [The effect of ultraviolet irradiation upon training for 100m sprint.] Fiziol Zh USSR. 1938;25:695-701.

[4] Lehmann G, Mueller EA. [Ultraviolet irradiation and altitude fitness.] Luftfahrtmedizin. 1944;9:37-43. [Article in German].

[5] Hettinger T, Muller EA.  Seasonal course of trainability of musculature.  Int Z Angew Physiol. 1956;16(2):90-4.

[6] Sigmund, R. The effect of ultra-violet rays on the human reaction time.  Strahlentherapie. 1956;101(4):623-9.

[7] Seidl E. [The effect of ultraviolet irradiation on reaction time.] Int Z Angew Physiol. 1958;17(4):333-40.

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Bright Light Therapy revs up the Sex Life.

By Marc Sorenson, EdD. Sunlight Institute…

At a meeting of the European College of Neuropsychopharmacology, a most interesting research report has emerged. The summary reads thusly: Exposure to bright light increases testosterone levels and leads to greater sexual satisfaction in men with low sexual desire. These are the results of a pilot randomised placebo-controlled trial.[i]

Men with low sexual desire were put in two groups; one group received bright light therapy from a light box; the other was treated with a light box that was not nearly so bright. Testosterone levels were measured in both groups. The experiment lasted two weeks, and the results were impressive. The men who had received the bright light therapy increased their sexual satisfaction scores increased by 300%. Testosterone levels also increased by 300% in the bright light group. The researchers believe that bright light therapy might have fewer side effects than drugs and offer at least equal results.

These results should not have been surprising. Long ago, light treatments were shown to remarkably increase testosterone levels. In 1939, Dr. Abraham Myerson measured initial levels of circulating testosterone in men and exposed their various body parts to UV.[ii] After five days of chest exposure sufficient to cause reddening, circulating testosterone increased by 120%. After eight days without additional UV exposure, testosterone returned to initial levels.  When the genital area was exposed, testosterone levels increased by 200%! Considering our sex-obsessed society, it is surprising that no studies followed up on Myerson’s work. Testosterone, after all, is important in sexual behavior, since it is the “love” hormone for both sexes.

 

If this information reaches the public, the interest in sunbathing may increase. That would be terrific, because sun exposure would also profoundly enhance the health of those who were soaking up the sun.

Is there anything that sun exposure can’t do? Just be careful not to burn in the sun.

[i] https://www.sciencedaily.com/releases/2016/09/160918214443.htm

[ii] Myerson, A.  Influence of ultraviolet radiation on excretion of sex hormones in the male.  Endocrinology 1939;25:7-12.

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New Research paper states that Sun exposure is less dangerous than vitamin D supplements.

In a new scientific paper, Dr. MS Razzaque shows that there may be some downsides to vitamin D supplementation, including “cardiovascular events and beyond.” He also states that “since hypovitaminosis D status usually reflects reduced sunlight exposure, the obvious primary replacement should be safe sunlight exposure, and not exogenous supplements.”[1]

The paper specifically mentions that avoiding sunlight exposure may influence the initiation and progression of different types of tumors [cancer], high blood pressure, type 1 diabetes and multiple sclerosis. It also points out that there may be some deleterious consequences of vitamin D supplementation, although in my opinion, the dosage would need to by quite high.

As I have indicated in many of my posts on the Sunlight Institute site, sun exposure is the most natural way to obtain vitamin D, and it has no toxicity, since it is self-regulated.

What wasn’t mentioned was the production of health-promoting substances when sun touches the skin, e.g. endorphins and nitric oxide. And of course, the sun helps the brain to produce serotonin and BDNF, which are critical for proper brain function.

So soak up your sunlight but don’t burn.

[1] Razzaque MS. Sunlight exposure: Do health benefits outweigh harm? J Steroid Biochem Mol Biol. 2016 Sep 16. [Epub ahead of print].

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More Research shows that Sun Exposure thwarts Multiple Sclerosis (MS).

By Marc Sorenson, EdD. Sunlight institute… sun exposure

 

If only those who suffer from MS had known the truth when they were younger! Getting plenty of sun exposure might have saved them from the ravages of this horrible disease. Much has been written about the influence of vitamin D on MS, and in this blog, I have pointed out that sun exposure may be more important than vitamin D. A new study conducted in Australia, and presented at the 32nd Congress of the European Committee for Treatment and in MS in Research in London, England, is interesting in the way it was conducted.[1]

By questionnaire, the researchers used past and present sun exposure as a surrogate for vitamin D levels and concluded that historical, but not current, vitamin D levels protect against MS.

This was an erroneous procedure to measure the influence of vitamin D levels on MS. It has already been established that sun exposure per se may be the operative habit that protects against MS. And in my opinion, vitamin D levels may only be surrogates for sun exposure, not vice versa. And, sun exposure probably mitigates MS, independent of vitamin D.

One of the most compelling papers on sun and MS was produced by Dr. Robyn Lucas and colleagues.[2] Here are the salient points in their report called Ultraviolet radiation, vitamin D and multiple sclerosis:

  • There is strong evidence from observational studies that low past sun exposure is associated with an increased risk of developing multiple sclerosis (MS).
  • Lower sun exposure or lower vitamin D status have been linked to more severe MS, that is, more frequent relapses and more rapid progression to disability.
  • Vitamin D supplementation trials for people with MS have shown improvement in immunological and MRI parameters, but with little convincing evidence of clinical benefit.
  • Higher levels of sun exposure may have benefits for MS-related immune parameters through both vitamin D and non-vitamin D pathways.
  • Exposure to ultraviolet radiation may result in immune tolerance that is beneficial for MS through upregulation of T and B regulatory cells, enhanced levels of cis-urocanic acid, alterations in dendritic cell trafficking as well as release of a range of other cytokines and chemokines.

To elucidate the last paragraph it is necessary to understand the vocabulary used. T cells are an integral part of the immune system that help rid the body of invading microorganisms. The regulatory T cells (or suppressor T cells) are a subpopulation of T cells which modulate the immune system and help prevent the body from attacking itself.[3] MS is another autoimmune disease in which the body is attacked its own immune system, which in the case of MS, destroys the myelin sheath. The regulatory, or T suppressor cells suppress these attacks, thereby preventing, abrogating or ameliorating the disease. B regulatory cells are also a part of the immune system and can, through their suppressive functions decrease inflammation, possibly through the production of anti-inflammatory cytokines.[4] Cis-urocanic acid is a chemical that is significantly lower in MS patients, and when stimulated by sun exposure, significantly reduces many indicators of MS.[5] [6] Dendritic cells are also messenger T cells that are essential in assisting sun exposure to decrease the immune response that effects autoimmune diseases.[7]

So let’s hear it for sun exposure as the very best therapy for MS. Be safe and don’t burn, and don’t use sunscreens, which can negate 99% of the sun’s vitamin D production.

[1] http://www.hcplive.com/conference-coverage/ectrims-2016/current-vitamin-d-doesnt-impact-ms-but-historical-exposure-does#sthash.ZF3nz3IN.dpuf

[2] Robyn M Lucas, Scott N Byrne, Jorge Correale, Susanne Ilschner & Prue H Hart. Ultraviolet radiation, vitamin D and multiple sclerosis. Neurodegener. Dis. Manag 2015 (epub ahead of print).

[3]https://en.wikipedia.org/wiki/Regulatory_T_cell (accessed November 24, 2015.)

[4] Min Yang, Ke Rui, Shengjun Wang and Liwei Lu. Regulatory B cells in autoimmune diseases. Cellular & Molecular Immunology (2013) 10, 122–132. Cellular & Molecular Immunology (2013) 10, 122–132.

[5] Jorge Correale and Mauricio Farez.S60 Multiple Sclerosis: Biomarkers: Clinical Phenotype Immune System Modulation in Multiple Sclerosis as a Result of Sun exposure: Role of cis-Urocanic Acid. Neurology April 6, 2012.  (names s

[6] Correale J, Farez MF. Modulation of multiple sclerosis by sun exposure: role of cis-urocanic acid. J Neuroimmunol. 2013 Aug 15;261(1-2):134-40.

[7] Breuer J, Schwab N, Schneider-Hohendorf T, Marziniak M, Mohan H, Bhatia U, Gross CC, Clausen BE, Weishaupt C, Luger TA, Meuth SG, Loser K, Wiendl H. Ultraviolet B light attenuates the systemic immune response in central nervous system autoimmunity. Ann Neurol. 2014 May;75(5):739-58.

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Sunscreen Dangers: Sunscreens may disrupt Progesterone Pathways and reduce Male Fertility.

By Marc Sorenson, EdD  Sunlight Institute… Sunscreen dangers..

Sperm count in men has dropped by more than half since 1950, possibly due to powerful chemicals that are finding their way into the water supply.[1] Now, the sperm that are still viable may have another problem, according to recent research: sunscreen chemicals are absorbed into the blood and carried into the sperm, which can render the sperm infertile.[2] [3] One investigation showed that an incredible 9% or more of the applied amount is absorbed through the skin.[4] Sunscreen chemicals also have potential “gender-bending” characteristics; they increase estrogen and decrease testosterone in men,[5] [6] and are also known to cause the feminization of fish. [7]And environmental pollution by these and similarly-structured chemicals are now thought to cause feminization in alligators and the gradual extinction of Florida panthers due to failure to breed.[8] Sunscreens also increase the absorption of pesticides through the skin. [9] [10] There are many more sunscreen dangers, but time and space will not permit us to discuss them all.

How does the system work to cause infertility? Many of the chemicals that filter out UV radiation can induce calcium signals in human sperm cells and mimic the effect of progesterone. This can render the sperm infertile. The aforementioned study that showed the influence of sunscreen chemicals was a lab study or “in vitro” investigation, using collected human sperm. It is not known if the same would happen in living human subjects, but it is likely.

These chemicals are known as endocrine disruptors, and with sperm count going down and many cancers increasing, they are not something I would recommend for public consumption.

Nature intends for us to cover up or seek the shade when we have had enough sun exposure. Nature also intends that we seek the sun to reap the benefit of it marvelous healthful benefits. Soak up the sun, but be sure not to burn. And don’t’ use sunscreens. There are too many sunscreen dangers, and they stop vitamin D production on the skin they cover.

[1] https://www.lifesitenews.com/news/study-finds-male-sperm-count-falling-dramatically-due-to-pollutants-in-wate.

[2] http://www.cnn.com/2016/04/14/health/sunscreen-sperm-male-fertility/index.html

[3] Rehfeld A, Dissing S, Skakkebæk NE

[4] Hayden CG, Roberts MS, Benson HA. Systemic absorption of sunscreen after topical application. Lancet 1997:350:863-64.

[5] Environmental Working Group: Americans Carry Body Burden of Toxic Sunscreen Chemical. March 25, 2008.  (available at http://www.ewg.org/node/26212).

[6] Ma R, Cotton B, Lichtensteiger W, Schlumpf M.  UV Filters with Antagonistic Action at Androgen Receptors in the MDA-kb2 Cell Transcriptional-Activation Assay.  Toxicological Sciences 2003;74:43-50.

[7] Kunz PY, Galicia HF, Fent K. Comparison of in vitro and in vivo estrogenic activity of UV filters in fish. Toxicol Sci 2006:90:349-61.

[8] Pickart, L.  The Chemical Sunscreen Health Disaster.  2000-2008.  (available at http://www.skinbiology.com/toxicsunscreens.html)

[9] Brand RM, Pike J, Wilson RM, Charron AR. Sunscreens containing physical UV blockers can increase transdermal absorption of pesticides. Toxicol Ind Health. 2003;19:9-16

[10] Pont AR, Charron AR, Brand RM. Active ingredients in sunscreens act as topical penetration enhancers for the herbicide 2,4 dichlorophenoxyacetic acid. Toxicol Appl Pharmacol. 2004;195:348-54.

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