Tag Archives: moles

What is the real cause of melanoma? It’s not sunlight!

What do you know about melanoma?melanoma is not caused by sun exposure

May is Melanoma Awareness Month, Therefore, we will discuss some truths to be aware of:

  • First of all, seventy-five percent of these cancers occur on areas of the body that are seldom or never exposed to sunlight.[1] For example, research has shown that melanomas in women occur primarily on the upper legs, and in men more frequently on the back—areas of little sun exposure.
  • Most noteworthy, in the U.S., sun exposure has decreased by about 90% since 1935. In the same time, melanoma incidence has increased by 3,000%! [2] [3] [4]

Dr. Diane Godar furnishes this exceptionally important melanoma information:[5]

  • The same as in the US, while sun exposure in Europe has profoundly decreased, there has been a spectacular increase in the disease.
  • Men who work outdoors have about half the risk as men who work indoors. Hence, sun exposure could not me the cause.
  • in addition, outdoor workers, while receiving 3-9 times the sun exposure as indoor workers, have had no increase in melanoma since before 1940, whereas the incidence in indoor workers has increased steadily and exponentially.
  • Especially relevant is that sunscreen invention, along with its steadily increasing use, has not reduced the risk of melanoma. Rather, the disease has increased as sunscreen use has increased.
  • Increasing melanoma incidence significantly correlates with decreasing personal annual sunlight exposure.
  • Also, outdoor workers get many sunburns but still have dramatically lower risk of contracting the disease.

So, since melanoma increases as sun exposure decreases, should we continue to blame the sun?

Here are more facts you should know about the causes of melanoma:

  • First of all, people in the highest quintile (fifth) of alcohol consumption have a 65% increase in risk.[6]
  • Weekly meat consumption increases the risk of melanoma by 84% and daily fruit consumption reduces the risk by nearly 50%.[7]
  • Furthermore, those with the highest levels of blood PCBs have 7-times the risk compared to those with the lowest levels.[8]
  • Recent use of Viagra is associated with an 84% increase in risk, and long-term use of the drug is associated with a 92% risk increase.[9]
  • Finally, there is a positive association between melanoma and obesity.[10]

Furthermore, Dr. Adele Green found that the strongest risk factor for both limb and trunk melanoma was moles. The presence of more than 10 moles on the arm predicted a 42-times increased risk.[11]

Therefore, please stop blaming the sun. Safely embrace the non-burning sun and reduce your risk of melanoma.

References:

[1] Crombie IK. Distribution of malignant melanoma on the body surface.Br J Cancer. 1981 Jun;43(6):842-9.

[2] Melanoma International Foundation, 2007 Facts about melanoma. Sources: National Cancer Institute 2007 SEER Database, American Cancer Society’s 2007 Facts and Figures, The Skin Cancer Foundation, The American Academy of Dermatology.

[3] Ian D. Wyatt and Daniel E. Hecker. Occupational changes in the 20th century. Monthly Labor Review, 2006 pp 35-57: Office of Occupational Statistics and Employment Projections, Bureau of Labor Statistics.

[4] US Congress, Office of Technology Assessment, Catching Our Breath: Next Steps for Reducing Urban Ozone, OTA-O-412 (Washington, DC: US Government Printing Office, July 1989).

[5] Stephen J Merrill, Samira Ashrafi, Madhan Subramanian & Dianne E Godar. Exponentially increasing incidences of cutaneous malignant melanoma in Europe correlate with low personal annual UV doses and suggests 2 major risk Factors. Dermato-endocrinology 2015;7:1

[6] Millen AE, Tucker MA, Hartge P, Halpern A, Elder DE, Guerry D 4th, Holly EA, Sagebiel RW, Potischman N. Diet and melanoma in a case-control study. Cancer Epidemiol Biomarkers Prev. 2004 Jun;13(6):1042-51.

[7] Gould Rothberg BE, Bulloch KJ, Fine JA, Barnhill RL, Berwick M. Red meat and fruit intake is prognostic among patients with localized cutaneous melanomas more than 1 mm thick. Cancer Epidemiol. 2014 Oct;38(5):599-607.

[8] Gallagher RP, Macarthur AC, Lee TK, Weber JP, Leblanc A, Mark Elwood J, Borugian M, Abanto Z, Spinelli JJ. Plasma levels of polychlorinated biphenyls and risk of cutaneous malignant melanoma: a preliminary study. Int J Cancer. 2011  15;128(8):1872-80.

[9] Li WQ, Qureshi AA, Robinson K, Han J. Sildenafil use and increased risk of incident melanoma in US men: a prospective cohort study. JAMA Intern Med. 2014 Jun;174(6):964-70C

[10] Karimi K, Lindgren TH, Koch CA, Brodell RT. Obesity as a risk factor for malignant melanoma and non-melanoma skin cancer. Rev Endocr Metab Disord. 2016 Sep;17(3):389-403.

[11] Green AC, Siskind V. Risk factors for limb melanomas compared with trunk melanomas in Queensland. Melanoma Res. 2012 ;22(1):86-91.

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Why Sun Exposure is Not Responsible for the Increase in Melanoma

melanoma is not caused by sun exposure

I have written several blogs making this melanoma case: not only is this deadly cancer not caused by sun exposure, but habitual, or regular, sun exposure has a protective effect against the disease. This blog will serve to reinforce and review the reasoning behind those conclusions.

A friend sent me a scientific paper[1] that I had forgotten or missed—a paper by Dr. Veronique Bataille that brought out several supportive points about how sun exposure protects against the disease. Here are a few of the salient ideas from the paper:

  1. The increase in melanoma is mostly seen for the thin types, which can’t be attributed to sun exposure but to increasing screening over the last 20 years. The fact is, that incidence appears to increase as the number of dermatologists and public health campaigns also increase. But the increase in melanoma is not real. This idea is perfectly plausible; when more dermatologists are available, and the public is driven to them by health campaigns more melanomas are found. Many “first-stage” or thin “thin” melanomas are discovered and counted that would not have been found in previous decades. This causes numbers to be highly inflated compared to the days when there were fewer dermatologists and fewer public health campaigns.

Comment: Another fact was not mentioned in the paper: Stunningly, a worldwide study of melanoma diagnosis and accuracy, published in the American Academy of Dermatology (AAD) showed that most diagnoses were incorrect.[2] Approximately 44 different authors from many different clinics and countries, including the US, contributed to the report. They made an accuracy-in-detection analysis based on the actual number of melanomas that were excised during a period of ten years, compared with the number that really needed to be excised.  Many clinics in different countries were involved in assessing the numbers. The AAD research showed that only about 3.5% of diagnoses in non-specialized clinics, and 14.7% in specialized clinics, resulted in actually being melanoma. From this information, it is evident that many melanoma surgeries are bogus and may inflate the incidence of this deadly skin cacner.

What do we take away from this? There may be no real increase in melanoma, only an increase in assessment and excision.

  1. Low vitamin D levels are common in melanoma patients and have a deleterious effect on their risk and survival.

Comment: Low vitamin D levels are caused by sunlight deprivation; we are told to avoid the sun, but sun avoidance leads to vitamin D deficiency, which further leads to melanoma. If our population regularly enjoyed non-burning sun exposure, vitamin D levels would be much higher and the risk of melanoma much lower. This is corroborated by the fact that people who habitually work outdoors have a far lower risk of the disease.  Dr. Cedric Garland and his colleagues showed that those who worked indoors had a 50% greater risk of  than those who worked both indoors and outdoors.[3]

  1. An excess of naevi (moles), not sun exposure, is the strongest risk factor for melanoma, and when comparing the risk created by sunburns and fair skin to the risk created by an excess of moles, the moles create a 15-30 times higher risk.

Comment:  Some very important research by Dr. Adele Green found that the strongest risk factor for both limb melanoma and trunk melanoma was the presence of more than 10 moles on the arm, which predicted a 42-times increased risk. [4]  This means that public health campaigns should promote mole awareness! Unfortunately, they promote sun avoidance, which increases the risk of melanoma.

  1. Attempts to decrease melanoma incidence and mortality, by reducing sun exposure, has not been proven to work and may be harmful.

Comment: the statement is obviously true. In the U.S., Sun exposure has decreased by about 90% since 1935. During that same period, melanoma has increased by 3,000%.[5] Data from the Bureau of Labor statistics showed that indoor occupations such as “professional, managerial, clerical, sales, and service workers (except private household service workers) grew from one-quarter to three-quarters of total employment between 1910 and 2000.” The BLS also stated, during the same period, the outdoor occupation of farming declined by 96% from 33% to 1.2% of total employment. The data also show approximately 66% of the decline in the occupation of farmers and 50% of the decline in the occupation of farm laborers occurred after 1935.

Further information, this time from the Environmental Protection Agency (EPA) determined as of 1986, about 5 percent of adult men worked mostly outside, and about 10 percent worked outside part of the time. The proportion of women who worked outside was thought to be even lower.[6] These data demonstrate a dramatic shift from outdoor, sun-exposed activity to indoor, non-sun-exposed activity during the mid-to-late 20th Century. This change, nonetheless, has been accompanied by a 30-times increase in risk since 1935, the MIF-baseline year.

  1. Photoageing, which is skin ageing due to sunlight exposure, is not greater in melanoma patients than patients who do not have the disease. In fact, patients with the cancer exhibit less photoageing than those who do not have the disease.

Comment: This was a new research for me and it belied the idea that sun exposure caused melanoma. If sun exposure causes skin photoageing, and there is less photoageing on cancer sites, sun exposure cannot possibly be causing melanoma. Enough said.

We need our sunshine, and one of the reasons for that need is to prevent deadly cancers.

[1] Bataille V. Melanoma. Shall we move away from the sun and focus more on embryogenesis, body weight and longevity? Medical Hypotheses 81 (2013) 846–850.

[2] Argenziano G, Cerroni L, Zalaudek I, Staibano S, Hofmann-Wellenhof R, et al. Accuracy in melanoma detection: a 10-year multicenter survey.J Am Acad Dermatol. 2012 Jul;67(1):54-9.

[3] Garland FC, White MR, Garland CF, Shaw E, Gorham ED. Occupational sunlight exposure and melanoma in the U.S. Navy. Arch Environ Health. 1990 Sep-Oct;45(5):261-7.

[4] Green AC, Siskind V. Risk factors for limb melanomas compared with trunk melanomas in Queensland. Melanoma Res. 2012 Feb;22(1):86-91.

[5] Melanoma International Foundation, 2007 Facts about melanoma. Sources: National Cancer Institute 2007 SEER Database, American Cancer Society’s 2007 Facts and Figures, The Skin Cancer Foundation, The American Academy of Dermatology.

[6] US Congress, Office of Technology Assessment, Catching Our Breath: Next Steps for Reducing Urban Ozone, OTA-O-412 (Washington, DC: US Government Printing Office, July 1989).

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