For Stopping Colon Cancer, Sunlight is far Superior to Vitamin D.

By Marc Sorenson, EdD, Sunlight Institute

Research now indicates that sunlight has very positive affects on colon cancer, whereas vitamin D has no affect, and in high doses may be counterproductive, at least in rats. Dr. AA Irving and colleagues performed a 140-day investigation involving rats that had colon adenomas (a precursor to full-blown colon cancer) induced in their colons.[1] The rats were given either vitamin D3, or the stored form, 25(OH)D3, in differing amounts. With low dose vitamin D in either form, no reduction in either existing adenomas or emerging tumors were seen. In higher doses, there was a dose-dependent increase in colon tumor numbers in both male and female rats.

The researchers said the following in their concluding statement: “Thus, the association between sunlight exposure and the incidence of colon cancer may involve factors other than vitamin D concentrations. Alternative hypotheses warrant investigation. Furthermore, this study provides preliminary evidence for the need for caution regarding vitamin D supplementation of humans at higher doses, especially in individuals with sufficient serum 25(OH)D3 concentrations.”

The takeaway from this research is that sunlight is protective against colon cancer in rats (and probably in humans), independent of vitamin D—another reason to embrace the sunlight (safely, of course).

[1] Irving AA, Plum LA, Blaser WJ, Ford MR, Weng C, Clipson L, DeLuca HF, Dove WF. Cholecalciferol or 25-hydroxycholecalciferol neither prevents nor treats adenomas in a rat model of familial colon cancer. J Nutr. 2015 Feb;145(2):291-8.

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Sleep Quality is improved by Exposure to Nature and Sunlight.

By Marc Sorenson, EdD, Sunlight Institute

A good, sound sleep is important to human health, both physical and mental. According to Dr. Diana Grigsby-Toussaint, “Studies show that inadequate sleep is associated with declines in mental and physical health, reduced cognitive function, and increased obesity.” She and her colleagues at the University of Illinois recently published a new study demonstrating that a natural environment may help people get the sleep they need.[1] The study showed that exposure to nature, which they dubbed “greenspace,” was associated with a more restful sleep. Other surroundings such as a sandy beach with an ocean view were also conducive to better sleep. One of the measurements used to qualify an area as greenspace was the availability of sunlight.[2]

I can attest to the fact that when I regularly walk through the pines and aspens located in the high mountains near my Nevada ranch, I sleep better at night. When I don’t get enough outdoor time in the trees and sunlight, I begin to suffer from what my friend, Dr. William Grant, calls nature-deficit disorder, or NDD. My whole mood is altered, and not for the better. Dr. Grant is not only a great sunlight scientist, but an avid birdwatcher, which takes him out daily do get his dose of nature.

We have a primal need for sunlight and natural surroundings, and too many city dwellers do not connect with sunlight and nature. Don’t fall into that trap. There is an adage that says, “What gets scheduled gets done.” Plan to be outside as often as possible and soak up some sun when it is available. Natural surroundings with sunlight are better than any psychiatrist or physician for maintaining mental and physical health.

[1] Grigsby-Toussaint DS, Turi KN, Krupa M, Williams NJ, Pandi-Perumal SR, Jean-Louis G. Sleep insufficiency and the natural environment: Results from the US Behavioral Risk Factor Surveillance System survey. Prev Med. 2015 Sep;78:78-84.

[2] http://news.aces.illinois.edu/news/u-i-study-men-people-over-65-sleep-better-when-they-have-access-nature.

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Anxious? Try a Little Sunlight.

By Marc Sorenson, EdD, Sunlight Institute

Are you suffering from anxiety disorder, but fear taking drugs?  Your fear is well-founded. It has been shown that a class of drugs called anti-anxiety drugs, i.e. valium and Xanax, and sleep aids like Ambien, Sonata and Lunesta lead to increased risk of death.[i] During 7.6 years, and after controlling for other factors such as sleep disorders, anxiety disorders and other psychiatric illnesses, it was found that the risk of dying was 3.46 times higher in those who took the drugs compared to those who did not. Considering the material we have posted on this site regarding brain disorders, insomnia, and sunlight, it seems reasonable to believe that a better and less dangerous anxiety-treatment option would be regular sunlight exposure.

Research from Denmark has shown that morning light, made to mimic daylight, relieves anxiety by reducing the activity of the brain’s fear center.[ii] The efficacy of the light treatment was based on the intensity of the light: the greater intensity, the greater the effect.

Another scientist, Dr Klaus Martiny, commented on the above study and noted that morning light improves sleep. “A lack of daylight disrupts some hormonal processes in our body that regulate our circadian rhythm. This can result in a shift in circadian rhythm, so that people go to sleep later and later in the evenings, and this shift is associated with an increased risk of depression.”[iii]

Martiny suggested that a good rule of thumb is to go to sleep before midnight and awaken before 8:00 AM. However, we discussed in the post on obesity that the earliest morning sunlight was associated with a remarkably lessened risk of obesity, which was also attributed to resetting the circadian rhythm. We therefore suggest that a better rule of thumb is to be outside for a half-hour when the sun rises each morning.

Get your morning sunlight, your midday sunlight and your afternoon sunlight. Sunlight is the great healer.

[i] Weich S, Pearce H, Croft P, Singh S, Crome L. et al. Effect of anxiolytic and hypnotic drug prescriptions on mortality hazards: retrospective cohort study. BMJ 2014;348:g1996.

[ii] Christensen B. Morning light relieves anxiety. Science Nordic 2014. http://sciencenordic.com/morning-light-relieves-anxiety Accessed August 8, 2015.

[iii] http://sciencenordic.com/morning-light-relieves-anxiety. Accessed August 8, 2015

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Beware the anti-depressant drugs. Use sunshine instead.

We have discussed the extraordinary ability of sunlight exposure or other bright-light exposure to profoundly increase the production of serotonin, a brain chemical that is a potent mood enhancer. The most remarkable research on this subject was by Dr. Gavin Lambert and his colleagues in Australia. They measured serotonin levels in response to varying degrees of bright light.[1] To do this, they actually took blood samples from internal jugular veins of 101 men and compared the serotonin concentration of the blood to weather conditions and seasons. The results were remarkable: MEN WHO WERE MEASURED ON A VERY BRIGHT DAY PRODUCED EIGHT TIMES MORE SEROTONIN THAN THOSE WHO WERE MEASURED ON A CLOUDY, DISMAL DAY. They also observed that the effect of bright light was immediate, and that there was no holdover from day to day. SEROTONIN LEVELS WERE ALSO SEVEN TIMES HIGHER IN SUMMER THAN WINTER. NO WONDER WE FEEL SO GOOD WHEN WE ARE OUTSIDE IN THE SUMMERTIME!

The most popular anti-depressant drugs also work by keeping serotonin levels higher, but there are frightening side-effects. The Food and Drug Administration (FDA), indicates that antidepressant medications known as selective serotonin re-uptake inhibitors (SSRI’s) may increase depression in some cases and lead to suicidal thoughts.  Some of the brands involved are Paxil, Lexapro, Prozac, Effexor, Zoloft, Wellbutrin, Luvox, Celexa and Serzone, although the FDA listed 34 drugs.  The entire list is at fda.gov/cder/drug/antidepressants/.  They state the following: “The Food and Drug Administration asks manufacturers of all antidepressant drugs to include in their labeling a boxed warning and expanded warning statements that alert health care providers to an increased risk of suicidality in children and adolescents being treated with these agents, and additional information about the results of pediatric studies.”

The FDA lists several additional warnings and instructions about these drugs:

  • Antidepressants increase the risk of suicidal thinking and behavior (suicidality) in children and adolescents with MDD (major depressive disorder) and other psychiatric disorders.

  • Anyone considering the use of an antidepressant in a child or adolescent for any clinical use must balance the risk of increased suicidality with the clinical need.

  • Patients who are started on therapy should be observed closely for clinical worsening, suicidality, or unusual changes in behavior.

  • Families should be advised to closely observe the patient and to communicate with the prescriber.

Missing are two important facts: (1) SSRI’s increase bone loss.[2] Women who used SSRI’s lose nearly 80% more bone per year than non-users! And as expected, later research shows that SSRI use correlated to a 75% greater likelihood of sustaining a fracture.[3] Secondly, SSRI’s don’t work very well. A meta-analysis of data on SSRI’s submitted to the FDA indicates that placebos (sugar pills) are as effective as SSRI’s in reducing depression; [4] in other words, only drug companies benefit from SSRI’s—not depression sufferers.

Based on that information, it seems prudent to increase our endorphins (and our happiness) through sunlight exposure. It is what nature intended.

 

[1] Lambert GW, Reid C, Kaye DM, Jennings GL, Esler MD. Effect of sunlight and season on serotonin turnover in the brain. Lancet. 2002 Dec 7;360(9348):1840-2.

[2] Diem SJ, Blackwell TL, Stone KL, Yaffe K, Haney EM, Bliziotes MM, Ensrud KE.. Use of antidepressants and rates of hip bone loss in older women; the study of osteoporotic fractures.  Arch Intern Med 2007:167:1231-32.

[3] Sheu YH, Lanteigne A, Stürmer T, Pate V, Azrael D, Miller M5. SSRI use and risk of fractures among perimenopausal women without mental disorders. Inj Prev. 2015 Jun 25. pii: injuryprev-2014-041483. doi: 10.1136/injuryprev-2014-041483. [Epub ahead of print]

[4] Kirsch, I. et al.  Initial severity and antidepressant benefits: a meta-analysis of data submitted to the Food and Drug Administration. PLoS Medicine 2008;5:e45.  doi:10.1371/journal.pmed.0050045

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More on the Effects of Sunlight beyond Vitamin D

By Marc Sorenson, EdD

Drs. Asta Juzeniene and Johan Moan wrote a paper in 2012 that beautifully summarizes the effects of sunlight beyond the production of vitamin D.[1] Here are the highlights of their paper, as stated in the abstract. They discuss the separate affects of Ultraviolet B light (UVB) and ultraviolet A light (UVA), which are, of course, components of sunlight.

  1. UVB induces cosmetic tanning (immediate pigment darkening, persistent pigment darkening and delayed tanning).
  2. UVB-induced, delayed tanning acts as a sunscreen.
  3. Several human skin diseases, like psoriasis, vitiligo, atopic dermatitis and localized scleroderma, can be treated with sunlight or artificial UV radiation (phototherapy).
  4. UV exposure can suppresses multiple sclerosis independently of vitamin D synthesis.
  5. UVA generates nitric oxide (NO), which may reduce blood pressure and generally improve cardiovascular health.
  6. UVA induced NO may also have antimicrobial effects.
  7. UVA induced NO may act as a neurotransmitter.
  8. UV exposure may improve mood through the release of endorphin.

It wasn’t mentioned in the paper, but we now know that sunlight also helps generate serotonin in the brain, which improves mood, and outside the body it is a potent disinfectant (see my recent blogs on those subjects). So those who claim that sunlight is harmful in any amount, must be living on a different planet. Embrace the Sun, but never burn.

[1] Asta Juzeniene and Johan Moan. Beneficial effects of UV radiation other than via vitamin D production. Dermato-Endocrinology 4:2, 109–117; April/May/June 2012.

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Sunlight and Cognition

By Marc Sorenson, EdD Sunlight Institute

We have previously discussed information indicating that people who received more sunlight had better brain function, and noted the relationship between Alzheimer’s, autism and other mental disorders and lack of sun. A recent study compared cognitive impairment and sunlight in a 15-year residential history of varying degrees of sunlight exposure. It showed that cognitive impairment in persons who were below the median exposure to sunlight was 88% greater than those who were above the median.[1]

The researchers mentioned vitamin D as a possible mechanism by which sunlight positively influenced cognition, but also remarked that regulation of the circadian rhythm by sunlight could be a factor. These same investigators had previously shown that lower levels of sunlight exposure resulted in a 2.58-times higher incidence of cognitive impairment.[2]

So, if you would like to maintain your cognitive abilities, soak up a little non-burning sunlight!

[1] Kent ST, Kabagambe EK, Wadley VG, Howard VJ, Crosson WL, Al-Hamdan MZ, Judd SE, Peace F, McClure LA. The relationship between long-term sunlight radiation and cognitive decline in the REGARDS cohort study. Int J Biometeorol. 2014 Apr;58(3):361-70.

[2] Kent ST, McClure LA, Crosson WL, Arnett DK, Wadley VG, Sathiakumar N. Effect of sunlight exposure on cognitive function among depressed and non-depressed participants: a REGARDS cross-sectional study. Environ Health. 2009 Jul 28;8:34

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Sunlight Exposure is Associated with a Reduced Risk of Stroke.

By Marc Sorenson, EdD, Sunlight Institute

Does sunlight have an influence on the risk of having a stroke? It does.

Interesting research had as an objective to determine whether long-term or short-term sunlight exposure affected stroke incidence.1  Measurements of sunlight exposures were taken for 15-,10-,5-,2-, and 1-year exposures to sunlight among 16,606 people who were free on any coronary disease. It was found that shorter exposure periods exhibited slightly stronger protective relationships against stroke, but both long- and short-term exposures were effective. Those who were below the median sunlight exposure had an increased risk of stroke of 61%. The researchers said that they did not know the biological pathways for the protective relationship, but I surmise that the answer is sunlight-induced nitric-oxide production, which keeps the blood pressure down and keeps the vessels flexible.

Whatever the mechanism by which sunlight protects us against stroke, let’s celebrate the fact that the protection is available.

1. Kent ST, McClure LA, Judd SE, Howard VJ, Crosson WL, Al-Hamdan MZ, Wadley VG, Peace F, Kabagambe EK. Short-and long-term sunlight radiation and stroke incidence. Ann Neurol. 2013 Jan;73(1):32-7.

 

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Sunlight and Food Allergy

By Marc Sorenson, EdD, Sunlight Institute

An August 15, 2015 review of research on sunlight, vitamin D and food allergy makes some interesting statements.[1] First, the researchers state that since 2007, most epidemiologic studies have supported low sunlight, as measured by season of birth and latitude, as a risk factor for food allergy. They then note that studies that looked directly at vitamin D status as measured by serum vitamin D levels are not nearly as consistent as the sunlight studies. They state: “Although conflicting, the vitamin D studies suggest a more complicated association than a linear dose response in all individuals, with some studies indicating different associations based on host characteristics (e.g. concomitant eczema, genetic polymorphisms, country of birth).”

Their summary is telling: “Many studies have linked sunlight with the development of food allergy but whether this is directly related to vitamin D status or a myriad of other sunlight-derived, seasonal and/or geographic factors remains uncertain. More studies are needed to investigate the role of sunlight and vitamin D status in food allergy because of their potential for primary prevention and disease modification.”

This is another of those scientific papers that illustrates that whereas sunlight exposure is nearly always protective against the studied disease, there is much more room for argument when vitamin D serum levels are used.

My takeaway? Get sufficient exposure to sunlight on a regular basis. That provides plenty of vitamin D when it is needed, but also provides nitric oxide, endorphins, serotonin, dopamine and other photoproducts that may yet be named. We must cease to equate sunlight exposure only with vitamin D production or we do a disservice to other healthful effects of sunlight.

 

[1] Rudders SA, Camargo CA Jr. Sunlight, vitamin D and food allergy. Curr Opin Allergy Clin Immunol. 2015 Aug;15(4):350-7.

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Viagra Use is Associated with a Profound increase in the Risk of Melanoma.

Recently, I posted that sunlight exposure, coupled with blueberry consumption, may be a better option than Viagra in terms of overcoming erectile dysfunction (ED)[1] but never mentioned that there might be a further association with Viagra and melanoma. Research now indicates a surprising newcomer to the melanoma equation: the use of sildenafil (Viagra) increases the invasiveness of melanoma cells, which may raise the risk of the disease.[2] In a study that was begun in 2000 and reported in 2014, it was found that recent use of Viagra was associated with an 84% increased risk of melanoma and that ever use of the drug was associated with a 92% risk. And among those who had no major chronic diseases at baseline, the risk was 124% higher for those who recently used the drug and 177% higher among those who had ever used the drug.

Noxious chemicals have many side effects, but who would have guessed that an ED drug would increase the risk of melanoma? Remember also that we have presented information showing that melanoma is not caused by regular sunlight exposure, and that sunlight is in fact protective against that disease. Sunlight, therefore, is a better choice for the prevention of both melanoma and ED.

[1] http://sunlightinstitute.org/sunshine-blueberries-nitric-oxide-and-peak-sexual-function-better-than-viagra-and-cialis/

[2] Li WQ, Qureshi AA, Robinson K, Han J. Sildenafil use and increased risk of incident melanoma in US men: a prospective cohort study. JAMA Intern Med. 2014 Jun;174(6):964-70C

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Sunlight Exposure Reduces the Risk of Heart Disease and does not Increase the Risk of Melanoma.

By Marc Sorenson, EdD, Sunlight Institute

An article in a South-East Asia online paper[i] has some good points on sunlight and disease, but is sullied by some unfortunate quotes by two people that I have great respect for, Drs. Richard Weller and Robyn Lucas. The article starts well enough by stating that health benefits of sun outweigh the risks. A statement by Dr. Weller is then quoted: “Dermatologists only think about the skin whereas the benefits of sunlight are predominantly in general health rather than skin health,” So far, so good. He also says that vitamin D tablets will not provide the same benefits as sunlight. That is also true.

Next, Dr. Weller says that the only major problem caused by sunlight is melanoma, but melanoma is often linked to sunburns that occur in childhood. The fact is, melanoma is not caused by sunlight, as I have reiterated in this blog many times. As people have moved out of the sunlight in the U.S., the risk of melanoma has increased exponentially; outdoor workers have a fraction or the risk of melanoma as indoor workers, and melanoma has increased only in indoor workers since 1940.

Later in the article, in trying to explain why melanoma incidence is low in South-East Asia, Dr. Lucas makes this statement: “this is probably due to the culture of not being sun-seeking in South-East Asia as well as a small contribution from having generally slightly darker skin. Even though the UV levels are high in these countries close to the equator, the burden of UV-related skin diseases is low” [italics mine]. Dr. Lucas has obviously bought into the idea that sunlight causes melanoma and must look for a reason to explain the fact that high sunlight exposure in South-East Asia associates with a low risk of the disease. In the italicized statement above she has answered the question. The reason that there is a low risk of melanoma in the area is because regular, high sunlight exposure prevents melanoma.

Nevertheless, the article is well-written until the last paragraph, which quotes a Dr. Emilie van Deventer:  “Sunlight exposure for the purposes of vitamin D is better earlier in the morning or later in the afternoon when the risk of skin damage caused by UV is much lower.” Anyone who makes such a statement has not read the research; almost no vitamin D is produced in early morning or late evening. Early-morning sunlight, of course, is associated closely with slimmer bodies, but not due to vitamin D.

So, I continue to fight this battle, separating the truth from the fiction, the gold from the dross. Regular, non-burning sunlight is good for us. Enjoy it safely and do not burn.

Read the article here: http://www.scidev.net/asia-pacific/health/news/sunlight-good-for-the-heart-researchers-say.html

[i] http://www.scidev.net/asia-pacific/health/news/sunlight-good-for-the-heart-researchers-say.html

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