Tag Archives: nitric oxide

Want to get Pregnant? Look to the Sun. Sunlight Exposure Increases Success Rate with IVF and may help with Problems of ED.

Marc Sorenson, EdD, Sunlight Institute

The Daily Mail, from the UK, recently posted an article regarding sunlight and fertility that should catch some interest.[1]

Infertility is a problem that causes some couples to seek help from in vitro fertilization (IVF). New research shows that sunlight exposure for a month prior to the procedure increase the odds of success by 35%.[2] Dr. Frank Vandekerckhove, who reported the research, looked at the IVF results of about 6,000 women and compared the dates of their treatment with weather conditions. The more sunshine, the greater likelihood of becoming pregnant. Dr. Vandekerckhove said that sunshine a month before conception probably helped a woman’s eggs to mature. He also mentioned that there is no reason to think that a burst of sunshine won’t also help women trying to get pregnant naturally.

There is nothing really new about the effects of sunlight on fertility, and this work by Vandekerckhove is not the first to establish the link of sunlight to IVF. Much has also been studied regarding natural, non- laboratory fertility. Low vitamin D, which is primarily a result of low sunlight exposure, is closely related to the ability to conceive in both women and men.  Couples spend thousands of dollars on fertility clinics and IVF when perhaps all they need is some time in the sun.

In an article posted on Emax health, entitled Sex in the Sun May Increase Your Fertility it is pointed out that approximately 15% of couples who want to conceive are plagued by problems of fertility.[3] Drs. Elisabeth Lerchbaum and Barbara Obermayer-Pietsch, in 2012, conducted a review of articles on vitamin D and fertility and came to these conclusions:[4] “VDR knockout mice [mice whose vitamin D doesn’t work due to inability to link to receptors at the cellular level] have significant gonadal insufficiency, decreased sperm count and motility, and histological abnormalities of testis, ovary and uterus.” They also point out that vitamin D is involved in female reproduction—including IVF outcome, so it is a bit surprising that the article in the Daily Mail gave the impression that the research by Vandekerckhove was a totally new concept.

The review also stated that in men, higher vitamin D levels are positively associated with semen quality and androgen (male hormone) status, and that vitamin D treatment might increase testosterone levels.

One thing that is missing in these excellent studies is any discussion of the production of nitric oxide (NO) by sunlight exposure. NO is a potent vasodilator that is essential for proper erection in men, meaning it relaxes the blood vessels, allowing the blood to pass more easily through the vessels. Without it erectile dysfunction (ED) occurs.[5] Viagra, Cialis and other such ED drugs work through a Nitric Oxide pathway[6] and act by keeping NO in circulation for a longer period. But they don’t work in about one-third of the cases, and the effect diminishes over time, not to mention the side effects such as headaches, body aches and pains, gastrointestinal distress, dizziness, vision changes, flushing, congestion and runny nose.[7] Since sunlight exposure increases NO, it is probably a better choice. For those who wish to produce a pregnancy, ED could be a devastating problem, and sunlight may be the answer.

Sunlight exposure has so many positive properties that we may never know them all. Use non-burning sunlight safely. Here’s to a successful pregnancy and a sunny family life!

[1] http://www.dailymail.co.uk/health/article-3130616/Sunbathing-help-pregnant-Increased-exposure-raise-odds-mother-third.html

[2]Vandekerckhove, F. Presentation at the European Society of Human Reproduction and Embryology (ESHRE) annual conference in Lisbon, Portugal, from June 14 to 17.

[3] http://www.emaxhealth.com/8782/sex-sun-may-increase-your-fertility

[4] Lerchbaum E1, Obermayer-Pietsch B. Vitamin D and fertility: a systematic review. Eur J Endocrinol. 2012 May;166(5):765-7.

[5] Burnett AL. The role of nitric oxide in erectile dysfunction: implications for medical therapy. J Clin Hypertens (Greenwich). 2006 Dec;8(12 Suppl 4):53-62.

[6] http://drliesa.com/neo-40-lozenges/

[7] http://www.healthline.com/health-slideshow/erectile-dysfunction-medications-common-side-effects?stickyLb=true

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Sunlight is better than Vitamin D in Preventing Weight Gain.

Marc Sorenson, EdD, Sunlight Institute

Those of you who follow this blog remember that one of my posts regarding weight control showed that early-morning sunlight was inversely correlated to body weight and Body Mass Index (BMI).[1] The earlier in the day the sunlight exposure occurred, the slimmer was the figure or physique.[2]

Another scientific paper was recently published that “sheds more light” on the subject of obesity. This research was conducted on mice that were placed on a high-fat diet and then exposed to non-burning ultraviolet radiation (UVR) during a three-month experiment.[3] The mice, without the benefit of UVR, would have been expected to gain weight rapidly, but when they were exposed to UVR, the weight gain was impressively reduced; the UVR treatment achieved 30-40% less weight gain, compared to the expected weight gain with the high-fat diet. The amount of UVR exposure to the mice was proportionally equal to the amount of UVR that a human would be exposed to by standing for ten minutes at noon.

Other benefits included significant reductions in glucose intolerance, insulin resistance and fasting insulin levels (all markers and predictors of diabetes), nonalcoholic fatty liver disease measures and cholesterol. All of these factors, including obesity, are part of a cluster of maladies known as the metabolic syndrome, or MetS, which is indicative of deteriorating health and susceptibility to heart disease, diabetes and death. 

Other interesting findings:

Supplementation with vitamin D actually reduced the aforementioned beneficial effects. Dr. Shelley Gorman, one of the authors, made two interesting observations regarding the research:

  1. “These findings were independent of circulating vitamin D and could not be mimicked by vitamin D supplementation.”[4]
  2. “It looked like the presence of vitamin D in mice on the high fat diet prevented the [beneficial] effect of UV radiation on weight gain.”
  3. She also mentioned that the mechanism or weight loss may be dependent on nitric oxide (NO), which originates from diet and can be mobilized by UV radiation to become bioactive.[5]

In another part of the experiment, skin induction of nitric oxide (NO)—also a product of skin exposure to sunlight—reproduced many of the positive effects of UVR, something that vitamin D could not do.

The authors concluded their research thusly: “These studies suggest that UVR (sunlight exposure) may be an effective means of suppressing the development of obesity and MetS, through mechanisms that are independent of vitamin D but dependent on other UVR-induced mediators such as NO.

Research continues to mount about the positive effects of sunlight that are independent of vitamin D. This should in no way be construed to diminish the vital importance of vitamin D; rather, it is to make a point that sunlight works in many ways, among which are stimulating the production vitamin D, stimulating the production of NO, stimulating the production of serotonin and stimulating the production of endorphins. Why should we be satisfied with any one of these marvelous health aids when sunlight is available? With sunlight exposure, we can have them all.

 

[1] http://sunlightinstitute.org/675/

[2] Reid KJ, Santostasi G, Baron KG, Wilson J, Kang J, Zee PC. Timing and intensity of light correlate with body weight in adults. PLoS One. 2014 Apr 2;9(4).

[3] Geldenhuys S, Hart PH, Endersby R, Jacoby P, Feelisch M, Weller RB, Matthews V, Gorman S. Ultraviolet radiation suppresses obesity and symptoms of metabolic syndrome independently of vitamin D in mice fed a high-fat diet. Diabetes. 2014 Nov;63(11):3759-69

[4] http://www.sciencewa.net.au/topics/health-a-medicine/item/3618-sun-shines-light-on-obesity-challenge

[5] See footnote 4.

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Working in Natural Light Improves Mood, Performance, Behavior and Psychological Health.

By Marc Sorenson, EdD.  Sunlight Institute

There are few things that improve our wellbeing like arising early in the morning and walking outside on a bright, sunny day. Our attitude improves, our serotonin and endorphin levels increase and there is an almost immediate feeling of exhilaration. We also become less confrontational, and our minds seem to click on all cylinders. Later on, around midday, if we are fortunate enough to have time to safely sunbathe (with lots of skin exposed), we produce large quantities of vitamin D, and our nitric oxide levels increase. This gives us a delicious feeling of relaxation and an almost instantaneous lowering of blood pressure as the cares of the day melt away.

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