UVB is a spectrum of sunlight with many effects. These include the suppression of inflammation in the skin. It has been used to very successfully treat skin diseases such as psoriasis and eczema.
Since inflammation is necessary to produce the condition of atherosclerosis (plugging of the arteries). It would be interesting to know whether UVB might also have the same anti-inflammatory effects in the arteries. If so, the effect could inhibit or eliminate atherosclerosis, and thus provide an entirely new treatment for heart disease. It would also protect against vascular events such as stroke and intermittent claudication.
The idea that UVB could prevent atherosclerosis by reducing inflammation in arteries was recently studied by Japanese researchers.[i] Using a mouse model, they demonstrated that UVB light irradiation, applied once a week for 14 weeks, leads to an increase in the action of T-regulatory cells, thereby inhibiting inflammation. In addition, exposure reduced the production of another type of T-cell which is pro-inflammatory and thereby pro-atherogenic (leading to the production of atherosclerosis). These two effects of UVB light reduce the development and progression of atherosclerosis.
Stated differently, the research shows that sun exposure is a critically-important therapy to reduce and prevent diseases of the heart and blood vessels. Protect your heart by being sure to obtain sufficient non-burning sunlight from sun exposure or other sources such as sun lamps. It is also important to note that neither skin cancer nor skin inflammation were observed following UVB exposure in this breakthrough study, which again emphasizes the importance of sun exposure for human health.
If these findings are true, then we would expect that there would be fewer cardiovascular events such as heart attacks and strokes during times of less sun exposure. Accordingly, Research has demonstrated that those below the median level of serum vitamin D suffer 57% more heart attacks than those whose levels were above the median[i] (low vitamin D levels are a surrogate for sun exposure). They also noted that the greatest number of heart attacks occurred in winter and early spring. These seasons, of course, are the times of lowest sun exposure. And, according to what we have learned, they are also the times of greatest inflammation.
Let there be light, and safely apply it to your skin. Be sure not to burn.
[i] Scragg R, Jackson R, Holdaway IM, Lim T, Beaglehole R. Myocardial infarction is inversely associated with plasma 25-hydroxyvitamin D3 levels: a community-based study. Int J Epidemiol 1990;19:559-63.
[i] Sasaki N, Yamashita T, Kasahara K, Fukunaga A, Yamaguchi T, et al. UVB Exposure Prevents Atherosclerosis by Regulating Immunoinflammatory Responses. Arterioscler Thromb Vasc Biol. 2016;36:00-00
UVB exposure benefits by Marc Sorenson, EdD. Sunlight Institute…
UVB is a spectrum of sunlight that is responsible for stimulation of vitamin D production in the skin. It also has many other effects, including the suppression of inflammation in the skin, and thus has been used to very successfully treat skin diseases such as psoriasis and eczema.[1] [2] [3] [4]
Since inflammation is also necessary to produce the condition of atherosclerosis (arterial plugging or occlusion) in arteries, it would be interesting to know whether UVB light might also have the same anti-inflammatory effects in those arteries. If so, the UVB effect could inhibit or eliminate atherosclerosis, and by so doing provide an entirely new treatment for heart disease and other vascular events such as stroke and intermittent claudication.
The idea that UVB could prevent atherosclerosis by reducing inflammation in arteries was recently studied by Japanese researchers.[5] [6] Using a mouse model, they demonstrated that UVB light irradiation, once weekly for 14 weeks, leads to an increase in the action of T-regulatory cells that inhibit inflammation. In addition, UVB exposure also reduced the production of another type of T-cell that is pro-inflammatory, and thereby proatherogenic (leading to the production of atherosclerosis). These two effects of UVB light reduce the development and progression of atherosclerosis. Or stated differently, the research shows that sun exposure is critically-important therapy to reduce and prevent heart and other vascular diseases.
Protect your heart by being sure to obtain sufficient non-burning UVB light from sun exposure or other sources such as the UVB lamps used by the researchers. It is important to note that neither skin cancer nor skin inflammation were observed following UVB exposure.
This is another breakthrough study that emphasizes the necessity of sun exposure for human health.
[1] National Psoriasis Foundation web site Oct. 2005.
[2] Yelverton CB, Kulkarni AS, Balkrishnan R, Feldman SR. Home ultraviolet B phototherapy: a cost-effective option for severe psoriasis. Manag Care Interface 2006;19:33-36, 39.
[3] Situm M, Bulat V, Majcen K, Dzapo A, Jezovita J. Benefits of controlled ultraviolet radiation in the treatment of dermatological diseases. Coll Antropol. 2014 Dec;38(4):1249-53.
[4] Gupta A, Arora TC, Jindal A, Bhadoria AS. Efficacy of narrowband ultraviolet B phototherapy and levels of serum vitamin D3 in psoriasis: A prospective study. Indian Dermatol Online J. 2016 Mar-Apr;7(2):87-92.
[5] Naoto Sasaki, Tomoya Yamashita, Kazuyuki Kasahara, Atsushi Fukunaga, Tomoyuki Yamaguchi, et al. UVB Exposure Prevents Atherosclerosis by Regulating Immunoinflammatory Responses. Arterioscler Thromb Vasc Biol. 2016;36:00-00.
DOI: 10.1161/ATVBAHA.116.308063.)
[6] Hafid Ait-Oufella, Andrew P. Sage. Editorial. The Sunlight. A New Immunomodulatory Approach of Atherosclerosis. (Arterioscler Thromb Vasc Biol. 2017;37:7-9. DOI: 10.1161/ATVBAHA.116.308637.)